38th Scientific Meeting (GV - SOLAS)
Society for Laboratory Animal Science

Seminar on Isolated Perfused Organs
(Essen, 2000)
     
   


  General Aspects  
  Mucous Membrane  
  Skin  
  Lung  
  Udder  
  Bone  
  Kidney  
  Liver  
  Uterus
 
  Intestines  


  Website sponsored by  
  Laboratory Animal Ltd  
  www.lal.org.uk  
   
 
 



Conference

Scientific Programme

38th Scientific Meeting of the Society of Laboratory Animal Science (GV-SOLAS) September 11 - 14, 2000

University Clinic Essen
Central Animal Laboratory

Time Course Essen 2000

September 11, 2000; Institute gruppe 1 - IG 1:


10.30-10.35 h Opening
10.35-11.00 h The ´with blood perfused pig ear´; a model for studying interactions between chemicals and the skin.
Elliott Graham R.; Dept. Pharmacology, TNO Prins Maurits Laboratorium, Postbus 45, 2280 AA, Rijswijk, NL
11.00-11.15 h The isolated haemoperfused porcine liver - Effects of Polidocanol and Diclofenac
Pfeffer J., Wevers P., Leiterer K., Nagel S., Große-Siestrup C.et al. Institute of Transfusion Medicine and Immunhaematology and Animal Experimental Facilities of Charite´, Campus Virchow Klinikum, Humboldt University, Berlin, Germany
11.15-11.30 h Cost-effective screening for oral bioavailability using the isolated perfused rat intestine
Nicholas D. Kerwin, Stuart G. Wood, BioDynamics Research Limited, Milton Keynes, Bucks, U.K.
11.30-11.45 h C O F F E E   B R E A K
11.45-12.00 h Effects of Different Perfusates on Functional Parameters of Isolated Perfused Dog Kidneys
Höchel J., Lehmann D., Große-Siestrup C. Fehrenberg C., and H. Hartmann Institute of Transfusion Medicine and Immunhaematology and Animal Experimental Facilities of Charite´, Campus Virchow Klinikum, Humboldt University, Berlin, Germany
12.00-12.15 h Isolated Pig Kidney Perfusion: 4-hour-cold-Preservation Superior to Fresh Harvested Unpreserved
Unger V., von Baeyer H., Große-Siestrup C. Institute of Transfusion Medicine and Immunhaematology and Animal Experimental Facilities of Charite´, Campus Virchow Klinikum, Humboldt University, Berlin, Germany
12.15-12.30 h Renal Ischaemia-Reperfusion Injuries - Influence of Species and Age on Functional Parameters in the Isolated Perfused Kidney from Dogs and Pigs
Höchel J, Unger V, Dittrich S. Lehmann D. Große-Siestrup C. Fehrenberg, C. Harmann H., Institute of Transfusion Medicine and Immunhaematology and Animal Experimental Facilities of Charite´, Campus Virchow Klinikum, Humboldt University, Berlin, Germany
12.30-12.45 h New experiences with xenoperfusion by the use of a pig- to- human setting
Aslan T, Grosse- Siestrup C, Unger V, von Baeyer H., Salama A Institute of Transfusion Medicine and Immunhaematology and Animal Experimental Facilities of Charite´, Campus Virchow Klinikum, Humboldt University, Berlin, Germany
12.45-13.00 h The isolated perfused canine leg used as a model studying the influx of drugs into the osseous tissue.
Vick M.,. Ehinger A.M. and Kietzmann M., Institute for Pharmacology, Pharmacy and Toxicology, Veterinary School Hannover, D-30559 Hannover
13.00-14.00 h L U N C H
14.00-14.30 h Isolated organ systems used in contract research labs
Heydeck D.; Mediport Biotechnik GmbH, D-12247 Berlin
14.30-14.45 h Tissue distribution of "systemically" administered antibiotics in the isolated perfused bovine udder
Ehinger A.M., Blume B. and Kietzmann M., Institute for Pharmacology, Pharmacy and Toxicology, Veterinary School Hannover, D-30559 Hannover
14.45-15.00 h The isolated perfused bovine uterus as a model for mucous membrane irritancy and inflammation
Bäumer W., Mertens A., Braun M., Kietzmann M., Institute for Pharmacology, Pharmacy and Toxicology, Veterinary School Hannover, D-30559 Hannover
15.00-15.15 h Assessment of the acute pulmonary toxicity of lamp oils (paraffin oil, Edenor ME 12 70, Edenor LPL) in perfused rat lungs
Uhlig S. and Göggel R., Division Pulmonary Pharmacology, Research Center Borstel, D-28845 Borstel
15.15-15.30 h In vitro studies on airway hyperreactivity in mice using isolated perfused lungs and precision-cut lung slices.
Held H.-D., Wohlsen A., Martin Ch. and Uhlig S., Division Pulmonary Pharmacology, Research Center Borstel, D-28845 Borstel
15.30-15.45 h C O F F E E  B R E A K
15.45-16.00 h An alternative investigation method for animal experiments in ischemia/reperfusion injury. The use of pig lungs and blood from slaughterhouse for isolated organ perfusion
v. Engelhardt A., Dittrich S., Lippek F., Hegemann O., Koios D., v.d. Gröben J., Grosse-Siestrup Ch. and Lange P. Department of Animal Experiments, the Pathological Institute, Charite´, Campus Virchow-Clinics and the Department of Congenital Heart Disease, Deutsches Herzzentrum, Berlin, Humboldt University of Berlin and Mediport Biotechnik Berlin
16.00-16.15 h The use of microdialysis technique for isolated perfused organs
Bäumer W., Kietzmann M., Institute for Pharmacology, Pharmacy and Toxicology, Veterinary School Hannover, D-30559 Hannover
16.15-16.30 h The use of the reflexion spectroscopy to study the distribution of carotinoids into the skin of the isolated perfused bovine udder
Niedorf F., Jungmann H., Pittermann W., Kietzmann M. Institute for Pharmacology, Pharmacy and Toxicology, Veterinary School Hannover, D-30559 Hannover, MBR Meßtechnik GmbH, D-58313 Herdecke, Henkel KGaA, D-40191 Duesseldorf
16.30-16.45 h Opportunities of the BUS-model during development and characterisation of transdermal systems using estradiol-17ß
Wolff M., Kluge K., Arth C., Bonn R. and Kietzmann M. Schwarz Pharma AG, Alfred-Nobel-Straße 10, D-40789 Monheim, Institute for Pharmacology, Pharmacy and Toxicology, Veterinary School Hannover, D-30559 Hannover
16.45-17.00 h In-vitro assay for the local compatibility in skin and mucous membranes: Testing of market products, ingredients, household- and process chemicals
Pittermann W., Förster T., B. Blume and Kietzmann M., Henkel KGaA, D-40191 Duesseldorf, Institute for Pharmacology, Pharmacy and Toxicology, Veterinary School Hannover, D-30559 Hannover


Official languages at the meeting: German and English

Fees:

Registration before July 31, 2000 DM 150,00 GV-SOLAS members
  DM 120,00 members of the IGTp
  DM 50,00 students
     
Registration after July 31, 2000 DM 250,00 GV-SOLAS members
  DM 200,00 members of the IGTp
  DM 75,00 students
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Additional Events

Sept. 11, 2000 Seminar “Isolated perfused organs as an alternative to animal experiments”
   
  Internet workshop “The use of data banks and other internet-resources to optimise animal experiments"
   
  Both events incur separate participation fees.
  The workshop is aimed primarily at animal protection officers. The number of participants is limited to a maximum of 30.
   
   
Sep. 12 - 14, 2000 Commercial Exhibition
   
  Programme of the Association of Animal Caretakers and Technical Personal (IGTp) (parallel to the main programme)
   
  For accompanying persons a sightseeing tour will be offered:
“Route of Industrial Heritage”
   
Sept. 14, 2000 Scientific excursion to the BAYER Research Centre Monheim (Farm Animal Centre and Tropicarium)
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Contact Addresses
August 6, 2000 Copyright © 2000 (UNI - Klinikum Essen, Prof. Dr. Klaus Militzer; Organization Committee)